The book was somewhat disappointing for me. Like many others, I have chronic pain (osteoarthritis, off and on lower back pain) and my wife does, too (Peripheral neuropathy). I was hoping to read about breakthroughs, promising treatments or at least experiments, in short, a beacon of hope. It is not that. The book is largely an outpouring of the author’s own experience as a chronic pain sufferer and as a pain doctor. It focuses largely on the psychological aspects, e.g. the difference between nociception (the biological process of detection of pain) and suffering, which is the broader mental effect the nociception has on the sufferer. There are many stories of individuals who experience chronic or severe pain (which are different things) but that becomes little more than a series of anecdotes. Some of it was interesting, but I believe the main purpose of the book is the catharsis the author felt in offloading his lifelong anguish.